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Compare Dog Spot Treatments
BIO SPOT ADVANTAGE FRONTLINE
TOP SPOT
FRONTLINE
PLUS
TRIFORCE
Manufacturer Farnam Bayer Merial Merial AgriLabs
Application topical spot-on topical spot-on topical spot-on topical spot-on topical spot-on
Contains Insect Growth Regulator X     X X
Kills Adult Fleas X X X X X
Repels Fleas X X     X
Kills Flea Eggs X     X X
Kills Flea Larvae   X   X X
Kills Ticks X   X X X
Kills Deer Ticks X   X X X
Repels Ticks X       X
Kills & Repels
Mosquitoes
X       X
Age Restrictions Over 6 months Over 7 weeks Over 10 weeks Over 8 weeks Over 12 weeks
Active Ingredient(s) 45% Permethrin &
S-Methoprene
Imidacloprid &
Permethrin
Fipronil Fipronil &
S-Methoprene
Cyphenothrin &
Pyriproxyfen
Treatments/
  Package
3 & 6 4 3 3 & 6 3
Remains efficacious
following bathing,
swimming or after
exposure to rain or
sunlight
  X X X X


Compare Cat Spot Treatments
BIO SPOT ADVANTAGE FRONTLINE
TOP SPOT
FRONTLINE
PLUS
TRIFORCE
Manufacturer Farnam Bayer Merial Merial AgriLabs
Application topical spot-on topical spot-on topical spot-on topical spot-on topical spot-on
Contains Insect Growth Regulator X     X X
Kills Adult Fleas X X X X X
Repels Fleas X X      
Kills Flea Eggs X     X X
Kills Flea Larvae   X   X X
Kills Ticks     X X X
Kills Deer Ticks X   X X X
Repels
Mosquitoes
X       X
Age Restrictions Over 12 weeks Over 8 weeks Over 12 weeks Over 8 weeks Over 12 weeks
Active Ingredient(s) Etofenprox &
S-Methoprene
Imidacloprid Fipronil Fipronil &
S-Methoprene
Etofenprox &
Pyriproxyfen
Treatments/
  Package
3 4 3 3 & 6 3
Remains efficacious
following bathing,
swimming or after
exposure to rain or
sunlight
  X X X X

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